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Table of Contents:

• Translating the knowledge of molecular alterations that occur during colon carcinogenesis into clinically relevant solutions
• Different pathways of colorectal carcinogenesis and their clinical pictures
• Control of β-catenin signaling in tumor development
• Genetic testing for familial adenomatous polyposis
• Molecular genetics of hereditary nonpolyposis colorectal cancer
• Pathology of hereditary nonpolyposis colorectal cancer
• Clinical aspects of hereditary nonpolyposis colorectal cancer
• Use of representational difference analysis and cDNA arrays for transcriptional profiling of tumor tissue
• CD44 acts both as a growth- and invasiveness-promoting molecule and as a tumor-suppressing cofactor
• The p53 tumor suppressor gene: from molecular biology to clinical investigation
• The epigenetics of colorectal cancer
• How does DNA methyltransferase cause oncogenic transformation?
• Altered mechanisms of apoptosis in colon cancer: fas resistance and counterattack in the tumor-immune conflict
• Translational studies on cox-2 inhibitors in the prevention and treatment of colon cancer
• Inhibition of CDKs as a therapeutic modality
• p53: a potential target antigen for immunotherapy of cancer
• Colorectal cancer vaccines: antiidiotypic antibody, recombinant protein, and viral vector
• Ga733/EpCAM as a target for passive and active specific immunotherapy in patients with colorectal carcinoma
• Radioimmunotherapy of colorectal cancer liver metastases: combination with radiotherapy.

Contributors:

Hanski, C. (Christoph), 1949-

Scherübl, Hans

Mann, B. (Benno), 1962-

Languages:

English

Language Notes:

Item content: English

Related Series:

Annals of the New York Academy of Sciences; v. 910

Subjects:

Colon (Anatomy) — Cancer — Molecular aspects — Congresses

Rectum — Cancer — Molecular aspects — Congresses

Colon (Anatomy) — Cancer — Immunological aspects — Congresses

Rectum — Cancer — Immunological aspects — Congresses

Colon (Anatomy) — Cancer — Molecular aspects

Colon (Anatomy)

Rectum — Cancer — Molecular aspects

Rectum

Colon (Anatomy) — Cancer — Immunological aspects

Rectum — Cancer — Immunological aspects

Genres:

Conference papers and proceedings

General Notes:

Includes bibliographical references and index.

Physical Description:

ix, 272 pages : illustrations ; 24 cm.

Call Numbers:

Q11 .N47 v.910

ISBNs:

1573312770 (cloth, acid-free paper)
1573312789 (paper)

Library of Congress Control Numbers:

00039443

OCLC Numbers:

43905882